Starter Assets in Pipeline
| Mechanism | Indication/ Mkt | Discovery | Pre-Clinical | Phase I | Phase II | Phase III | Launch | |
|---|---|---|---|---|---|---|---|---|
| VA106483 | V2 Agonist & Backups | BPH / Nocturia >$1bn potential |
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| VA111913 | V1a Antagonist & Backups | Dysmenorrhoea $multi bn |
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| VA118020 | KLK1 Inhibitor | Respiratory Disease $bns | ![]() |
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| KKI | Kallikrein Inhibitor Platform | Inflammatory Diseases $bns | ![]() |
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| FAP | FAP Platform | Oncology $bns | ![]() |
VA106483 is a Vasopressin agonist, currently being developed for the treatment of nocturia, this product is currently in Phase 2 stage of clinical trials.
VA111913 is a vasopressin antagonist, about to enter human trials (in 2008) for the treatment of dysmenorrhoea, a common condition in women of childbearing age. VA111913 acts directly on the uterus, and may represent the first of a new type of therapy for this debilitating condition.
VA118020 is a tissue kallikrein inhibitor that is in preclinical development for use in respiratory disorders. It is a first-in-class oral therapy.
KKI is a platform of compounds, the lead of which are entering pre-clinical development in 2008. The compounds work by inhibiting Kallikreins, in a very specific way - to reduce inflammation. These compounds are being developed for a variety of inflammatory diseases.
FAP is a platform of Fibroblast Activation Protein Inhibitors in lead discovery, these compounds have potential application in several Oncological & Fibrotic diseases.

